Brewer, wine and spirits merchant. Arrived in New South Wales in August 1843; With brother Edwin leased the Kent Brewery in Sydney from his uncle for 9 years and later purchased it. Brothers were wine and spirit merchants, imports of wine, beer and spirits being the firms principal source of profit. Firm known as Tooth & Co, from c.1853 when brother Frederick became a partner; changed name to R & F Tooth & Co., when J.S Mitchell joined partnership in 1860. Retired from firm in 1872. Director of Bank of New South Wales in 1850s and 1860s, president from 1862 until 1863; shareholder in unsuccessful Great Nugget Vein Gold Mining Company of Australia. Partner in London house of R & F Tooth & Mort, acting as agent for Sydney Marine Insurance Office and Peak Downs Copper Mining Company. Formed Twofold Bay Pastoral Association in 1852 which acquired 400,000 acres on the South Coast and Monaro. Speculated in pastoral properties in 1850s; disposed of squatting interests in New South Wales by 1860; Held runs in Queensland. In late 1850s had c.600 employees. Favourable to limited free selection, but opposed Robertson's land bills. Director of Society for Relief of Destitute Children. Prominent Anglican. Fellow of St Pauls College at University of Sydney. Foundation member of Committee Union Club.